CRISPR / Cas: the future of genetic editing
Since the project of the human genome and the subsequent publication of the sequence of more than 20,000 genes that comprise it, the study of the genomes of many organisms and their editing have been a trend since then, being proposed and discovered new tools that allow the editing of DNA. CRISPR/Ca...
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Universida de Sonora
2019
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oai:http:--epistemus.unison.mx:article-942021-07-29T02:22:56Z CRISPR / Cas: the future of genetic editing CRISPR/CAS: EL FUTURO DE LA EDICIÓN GENÉTICA Mayboca Padilla, Daniel Flores Ruiz, Daniel CRISPR/Cas Genomic editing tool Gene therapy Antiviral treatment CRISPR/Cas Edición genómica Terapia génica Tratamiento antiviral Since the project of the human genome and the subsequent publication of the sequence of more than 20,000 genes that comprise it, the study of the genomes of many organisms and their editing have been a trend since then, being proposed and discovered new tools that allow the editing of DNA. CRISPR/Cas system whose natural function is a defense of bacteria against viral infections, ended up being a breakthrough in the field of genomic sciences, allowing genomic editing at a level of precision greater than the techniques that preceded it. The applications of this system that has been emphasized in recent years, are gene therapy and the Development of alternative antiviral treatments. Despite the advances of CRISPR/Cas, it is still required to increase its specificity to eliminate the appearance of mutations outside the target gene. Desde el emprendimiento del proyecto del genoma humano y la posterior publicación de la secuencia de los más de 20,000 genes que lo comprende, el estudio de los genomas de muchos organismos, su manipulación y edición ha sido tendencia desde entonces, siendo propuestas y descubiertas nuevas herramientas que permiten la edición de los ácidos nucleicos. La función natural de CRISPR/Cas supone una defensa de las bacterias ante infecciones virales y terminó por ser un gran avance en el campo de las ciencias genómicas, permitiendo la edición genómica con mayor precisión al de las técnicas que le anteceden. Las aplicaciones de este sistema en las que se ha hecho énfasis en estos últimos años, son en la terapia génica y en el desarrollo de tratamientos antivirales. A pesar de los grandes avances de CRISPR/Cas, aún se requiere incrementar su especificidad para eliminar la aparición de mutaciones fuera del gen objetivo. Universida de Sonora 2019-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Research Investigación application/pdf https://epistemus.unison.mx/index.php/epistemus/article/view/94 10.36790/epistemus.v13i26.94 EPISTEMUS; Vol. 13 No. 26 (2019): Science does not stop; 36-41 EPISTEMUS; Vol. 13 Núm. 26 (2019): La ciencia no cesa; 36-41 2007-8196 2007-4530 spa https://epistemus.unison.mx/index.php/epistemus/article/view/94/68 https://creativecommons.org/licenses/by-nc-nd/4.0 |
| institution |
Epistemus |
| collection |
OJS |
| language |
spa |
| format |
Online |
| author |
Mayboca Padilla, Daniel Flores Ruiz, Daniel |
| spellingShingle |
Mayboca Padilla, Daniel Flores Ruiz, Daniel CRISPR / Cas: the future of genetic editing |
| author_facet |
Mayboca Padilla, Daniel Flores Ruiz, Daniel |
| author_sort |
Mayboca Padilla, Daniel |
| title |
CRISPR / Cas: the future of genetic editing |
| title_short |
CRISPR / Cas: the future of genetic editing |
| title_full |
CRISPR / Cas: the future of genetic editing |
| title_fullStr |
CRISPR / Cas: the future of genetic editing |
| title_full_unstemmed |
CRISPR / Cas: the future of genetic editing |
| title_sort |
crispr / cas: the future of genetic editing |
| description |
Since the project of the human genome and the subsequent publication of the sequence of more than 20,000 genes that comprise it, the study of the genomes of many organisms and their editing have been a trend since then, being proposed and discovered new tools that allow the editing of DNA. CRISPR/Cas system whose natural function is a defense of bacteria against viral infections, ended up being a breakthrough in the field of genomic sciences, allowing genomic editing at a level of precision greater than the techniques that preceded it. The applications of this system that has been emphasized in recent years, are gene therapy and the Development of alternative antiviral treatments. Despite the advances of CRISPR/Cas, it is still required to increase its specificity to eliminate the appearance of mutations outside the target gene. |
| publisher |
Universida de Sonora |
| publishDate |
2019 |
| url |
https://epistemus.unison.mx/index.php/epistemus/article/view/94 |
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