Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.

In this work Poly (lactic acid) (PLA) electrospun fibers added with Rumex hymenosepalus extract were prepared and characterized. A morphologic characterization study gave support to choose the parameters that allow the obtention of uniform fibers, within the parameters that was studied were rate flo...

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Autor principal:	Armenta Villegas, Lorena
Formato:	Online
Lenguaje:	eng
Publicado:	Universidad de Sonora 2020
Acceso en línea:	https://biotecnia.unison.mx/index.php/biotecnia/article/view/1224
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id	biotecnia-article-1224
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spelling	biotecnia-article-12242022-05-31T17:20:08Z Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization. Fibras electrohiladas de poli (ácido láctico) adicionadas con extracto de Rumex hymenosepalus: preparación y caracterización Armenta Villegas, Lorena electrospun poly (lactic acid) Rumex hymenosepalus wound dressings electrohilado hidrólisis antioxidante Rumex hymenosepalus In this work Poly (lactic acid) (PLA) electrospun fibers added with Rumex hymenosepalus extract were prepared and characterized. A morphologic characterization study gave support to choose the parameters that allow the obtention of uniform fibers, within the parameters that was studied were rate flow varied from 0.8-2.0 mL/h and voltage variation between 15-20 kV. The morphology of the electrospun nanofibers was examined by scanning electron microcopy, statistical study was made to identify the fibers diameters obtained with parameter modification. Since PLA is well known as hydrophobic material, an alkaline hydrolysis was performed to improve the interaction sites of the electrospun fiber and R. hymenosepalus extract. FTIR-ATR study was performed to evaluate the behavior of the PLA electrospun fibers and PLA hydrolyzed electrospun fibers and it´s interaction with the R. hymenosepalus extract. Antioxidant release study was carried out using UV-Vis spectroscopy and with this evaluation was determined that the alkaline treatment help to control the Rh release rate. The obtained results let the electrospun fibers of PLA-Rh were considered useful for antioxidant release applications like wound dressings. El método de electrohilado es ampliamente utilizado para desarrollar biomateriales útiles en medicina regenerativa. La adición de compuestos bioactivos a matrices poliméricas les confiere propiedades que fomentan su uso en aplicaciones biomédicas. En este trabajo se prepararon y caracterizaron fibras electrohiladas de Poli(ácido láctico) (PLA) adicionadas con extracto de Rumex hymenosepalus con el objetivo de obtener un material novedoso con uso potencial como apósitos para heridas. Se obtuvieron fibras utilizando distintos parámetros y se seleccionaron las fibras obtenidas utilizando un rotor con velocidad de flujo de 0.6 mL/h y 15 kV de voltaje para continuar el estudio. La morfología de las fibras se examinó por microscopia electrónica de barrido y se determinaron los diámetros promedio. Se realizó una hidrólisis alcalina para mejorar la interacción de las fibras electrohiladas y el extracto de R. hymenosepalus. El estudio FTIR-ATR permitió evaluar la interacción de las fibras de PLA y PLA hidrolizado con el extracto de R. hymenosepalus. Los resultados del estudio de liberación por espectroscopia UV-vis mostraron que la hidrólisis alcalina ayuda a controlar la velocidad liberación del R. hymenosepalus. Los resultados obtenidos muestran que las fibras PLA-R. hymenosepalus tienen posible utilidad en aplicaciones de liberación de antioxidantes como apósitos para heridas. Universidad de Sonora 2020-09-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Original peer-reviewed articles Artículos originales evaluados por pares application/pdf text/xml https://biotecnia.unison.mx/index.php/biotecnia/article/view/1224 10.18633/biotecnia.v22i3.1224 Biotecnia; Vol. 22 No. 3 (2020): Septiembre-Diciembre; 108-115 Biotecnia; Vol. 22 Núm. 3 (2020): Septiembre-Diciembre; 108-115 1665-1456 1665-1456 eng https://biotecnia.unison.mx/index.php/biotecnia/article/view/1224/462 https://biotecnia.unison.mx/index.php/biotecnia/article/view/1224/515 Derechos de autor 2020 Biotecnia
institution	Biotecnia
collection	OJS
language	eng
format	Online
author	Armenta Villegas, Lorena
spellingShingle	Armenta Villegas, Lorena Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.
author_facet	Armenta Villegas, Lorena
author_sort	Armenta Villegas, Lorena
title	Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.
title_short	Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.
title_full	Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.
title_fullStr	Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.
title_full_unstemmed	Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.
title_sort	poly (lactic acid) electrospun fibers added with rumex hymenosepalus extract: preparation and characterization.
description	In this work Poly (lactic acid) (PLA) electrospun fibers added with Rumex hymenosepalus extract were prepared and characterized. A morphologic characterization study gave support to choose the parameters that allow the obtention of uniform fibers, within the parameters that was studied were rate flow varied from 0.8-2.0 mL/h and voltage variation between 15-20 kV. The morphology of the electrospun nanofibers was examined by scanning electron microcopy, statistical study was made to identify the fibers diameters obtained with parameter modification. Since PLA is well known as hydrophobic material, an alkaline hydrolysis was performed to improve the interaction sites of the electrospun fiber and R. hymenosepalus extract. FTIR-ATR study was performed to evaluate the behavior of the PLA electrospun fibers and PLA hydrolyzed electrospun fibers and it´s interaction with the R. hymenosepalus extract. Antioxidant release study was carried out using UV-Vis spectroscopy and with this evaluation was determined that the alkaline treatment help to control the Rh release rate. The obtained results let the electrospun fibers of PLA-Rh were considered useful for antioxidant release applications like wound dressings.
publisher	Universidad de Sonora
publishDate	2020
url	https://biotecnia.unison.mx/index.php/biotecnia/article/view/1224
work_keys_str_mv	AT armentavillegaslorena polylacticacidelectrospunfibersaddedwithrumexhymenosepalusextractpreparationandcharacterization AT armentavillegaslorena fibraselectrohiladasdepoliacidolacticoadicionadasconextractoderumexhymenosepaluspreparacionycaracterizacion
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Poly (Lactic Acid) Electrospun fibers added with Rumex hymenosepalus extract: preparation and characterization.

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