Preventive Approach in Non-Alcoholic Fatty Liver Disease

Obesity is currently a worldwide public health problem. It is characterized by its negative impact on multiple organs, including the liver, through the development of diseases such as non-alcoholic fatty liver disease (NAFLD), which can promote the development of hepatocellular carcinoma. This revie...

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Autores principales: LÓPEZ-ALMADA, GABRIELA, DOMÍNGUEZ-AVILA, J. ABRAHAM, GONZÁLEZ-AGUILAR, GUSTAVO A., MEJÍA-LEÓN, MARIA ESTHER, SALAZAR-LÓPEZ, NORMA JULIETA
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Publicado: Universida de Sonora 2022
Acceso en línea:https://epistemus.unison.mx/index.php/epistemus/article/view/185
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spelling oai:http:--epistemus.unison.mx:article-1852023-06-14T01:03:40Z Preventive Approach in Non-Alcoholic Fatty Liver Disease Abordaje preventivo en la enfermedad por hígado graso no alcohólico LÓPEZ-ALMADA, GABRIELA DOMÍNGUEZ-AVILA, J. ABRAHAM GONZÁLEZ-AGUILAR, GUSTAVO A. MEJÍA-LEÓN, MARIA ESTHER SALAZAR-LÓPEZ, NORMA JULIETA OBESITY PUBLIC HEALT BIOACTIVE COMPOUNDS NON-ALCOHOLIC FATTY LIVER PREVENTIVE APPROACH OBESIDAD SALUD PUBLICA COMPUESTOS BIOACTIVOS HIGADO GRASO NO ALCOHOLICO PREVENCION PRIMARIA Obesity is currently a worldwide public health problem. It is characterized by its negative impact on multiple organs, including the liver, through the development of diseases such as non-alcoholic fatty liver disease (NAFLD), which can promote the development of hepatocellular carcinoma. This review discusses the association between obesity and the development of NAFLD, emphasizing on the importance of a preventive and interventional approach during the early stages of the disease, as well as the potential effect of some dietary bioactive compounds.  In this regard, it is advisable to focus the intervention on improving BMI, through a program of physical activity, nutritional and health education, and changes in dietary patterns. The inclusion of foods rich in bioactive compounds, such as phenolic compounds, fiber and vitamins can provide an antioxidant, anti-inflammatory and anti-obesogenic effect that could hinder the progression of NAFLD and other comorbidities and complication. La obesidad es actualmente un problema de salud pública a nivel mundial. Ésta se caracteriza por afectar a múltiples órganos, entre ellos el hígado, desarrollándose enfermedades como la enfermedad de hígado graso no alcohólico (EHGNA), la cual predispone al desarrollo de carcinoma hepatocelular. En esta revisión se discute la asociación entre la obesidad y la EHGNA, enfatizando un abordaje preventivo y de intervención en etapas tempranas de la enfermedad, así como los potenciales efectos de algunos compuestos bioactivos presentes en la dieta. Al respecto es recomendable centrar la intervención en mejorar el IMC, a través de un programa de actividad física, educación nutricional y de salud, y cambios en los patrones dietéticos. La inclusión de alimentos ricos en compuestos bioactivos, como los compuestos fenólicos, fibra y vitaminas pueden proveer de un efecto antioxidante, antiinflamatorio y anti-obesogénico que podrían obstaculizar la progresión de la EHGNA, y otras comorbilidades y complicaciones. Universida de Sonora 2022-04-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion CienTecYSoc CienTecYSoc application/pdf application/pdf text/xml https://epistemus.unison.mx/index.php/epistemus/article/view/185 10.36790/epistemus.v16i32.185 EPISTEMUS; Vol. 16 No. 32 (2022): Issue 32; 71-78 EPISTEMUS; Vol. 16 Núm. 32 (2022): Revista No. 32; 71-78 2007-8196 2007-4530 spa https://epistemus.unison.mx/index.php/epistemus/article/view/185/295 https://epistemus.unison.mx/index.php/epistemus/article/view/185/229 https://epistemus.unison.mx/index.php/epistemus/article/view/185/258 Derechos de autor 2022 EPISTEMUS https://creativecommons.org/licenses/by-nc-sa/4.0
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author LÓPEZ-ALMADA, GABRIELA
DOMÍNGUEZ-AVILA, J. ABRAHAM
GONZÁLEZ-AGUILAR, GUSTAVO A.
MEJÍA-LEÓN, MARIA ESTHER
SALAZAR-LÓPEZ, NORMA JULIETA
spellingShingle LÓPEZ-ALMADA, GABRIELA
DOMÍNGUEZ-AVILA, J. ABRAHAM
GONZÁLEZ-AGUILAR, GUSTAVO A.
MEJÍA-LEÓN, MARIA ESTHER
SALAZAR-LÓPEZ, NORMA JULIETA
Preventive Approach in Non-Alcoholic Fatty Liver Disease
author_facet LÓPEZ-ALMADA, GABRIELA
DOMÍNGUEZ-AVILA, J. ABRAHAM
GONZÁLEZ-AGUILAR, GUSTAVO A.
MEJÍA-LEÓN, MARIA ESTHER
SALAZAR-LÓPEZ, NORMA JULIETA
author_sort LÓPEZ-ALMADA, GABRIELA
title Preventive Approach in Non-Alcoholic Fatty Liver Disease
title_short Preventive Approach in Non-Alcoholic Fatty Liver Disease
title_full Preventive Approach in Non-Alcoholic Fatty Liver Disease
title_fullStr Preventive Approach in Non-Alcoholic Fatty Liver Disease
title_full_unstemmed Preventive Approach in Non-Alcoholic Fatty Liver Disease
title_sort preventive approach in non-alcoholic fatty liver disease
description Obesity is currently a worldwide public health problem. It is characterized by its negative impact on multiple organs, including the liver, through the development of diseases such as non-alcoholic fatty liver disease (NAFLD), which can promote the development of hepatocellular carcinoma. This review discusses the association between obesity and the development of NAFLD, emphasizing on the importance of a preventive and interventional approach during the early stages of the disease, as well as the potential effect of some dietary bioactive compounds.  In this regard, it is advisable to focus the intervention on improving BMI, through a program of physical activity, nutritional and health education, and changes in dietary patterns. The inclusion of foods rich in bioactive compounds, such as phenolic compounds, fiber and vitamins can provide an antioxidant, anti-inflammatory and anti-obesogenic effect that could hinder the progression of NAFLD and other comorbidities and complication.
publisher Universida de Sonora
publishDate 2022
url https://epistemus.unison.mx/index.php/epistemus/article/view/185
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