Diabetes mellitus and COVID-19: ¿A vicious cycle?

Diabetes mellitus and COVID-19 are global health issues that represent a challenge for health systems. Diabetes mellitus is a disease that is characterized by elevated glucose levels. COVID-19 is an infection caused by the virus SARS-CoV-2. Diabetes mellitus may increase the adverse outcome in patie...

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Autores principales: Flores-Díaz, Andrea, Hinojosa-Pérez, Botswana
格式: Online
语言:spa
出版: REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora 2021
在线阅读:https://ojs-remus.unison.mx/index.php/remus_unison/article/view/6
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总结:Diabetes mellitus and COVID-19 are global health issues that represent a challenge for health systems. Diabetes mellitus is a disease that is characterized by elevated glucose levels. COVID-19 is an infection caused by the virus SARS-CoV-2. Diabetes mellitus may increase the adverse outcome in patients with COVID-19. The main aim of the present systematic review was to summarize the principal known mechanisms that increment this vulnerability, highlighting special measures. The importance of this lies in the fact that a large proportion of the world's population is affected by diabetes mellitus. The studies achieved since the beginning of the pandemic on the association between these diseases are substantial, however, much remains to be known. The information available was consulted in spanish and english through a literature review in databases as PubMed, Google Scholar and journals like Lancet and Nature till June 18, 2021. The main keywords used were “Diabetes mellitus” “COVID-19”, “ACE 2” “Endothelial dysfunction” “Immune response” “Alveolar dysfunction” and “Pathophysiology”. The main alterations found were of the angiotensin-converting enzyme 2, dysregulated immune response, endothelial dysfunction, coagulopathy, treatment, and complications of diabetes mellitus. Therefore, these patients should pay special attention in the prevention of COVID-19 and the health systems must guarantee adequate treatment, attention, infrastructure, and services.