Diabetes mellitus and COVID-19: ¿A vicious cycle?
Diabetes mellitus and COVID-19 are global health issues that represent a challenge for health systems. Diabetes mellitus is a disease that is characterized by elevated glucose levels. COVID-19 is an infection caused by the virus SARS-CoV-2. Diabetes mellitus may increase the adverse outcome in patie...
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REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora
2021
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| Sarrera elektronikoa: | https://ojs-remus.unison.mx/index.php/remus_unison/article/view/6 |
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oai:ojs.remus.unison:article-62021-10-21T13:23:17Z Diabetes mellitus and COVID-19: ¿A vicious cycle? Diabetes mellitus y COVID-19: ¿Un ciclo vicioso? Flores-Díaz, Andrea Hinojosa-Pérez, Botswana Diabetes Mellitus COVID-19 Infección SARS-CoV-2 Factores de Riesgo Diabetes Mellitus COVID-19 Infection SARS CoV-2 Risk Factors Diabetes mellitus and COVID-19 are global health issues that represent a challenge for health systems. Diabetes mellitus is a disease that is characterized by elevated glucose levels. COVID-19 is an infection caused by the virus SARS-CoV-2. Diabetes mellitus may increase the adverse outcome in patients with COVID-19. The main aim of the present systematic review was to summarize the principal known mechanisms that increment this vulnerability, highlighting special measures. The importance of this lies in the fact that a large proportion of the world's population is affected by diabetes mellitus. The studies achieved since the beginning of the pandemic on the association between these diseases are substantial, however, much remains to be known. The information available was consulted in spanish and english through a literature review in databases as PubMed, Google Scholar and journals like Lancet and Nature till June 18, 2021. The main keywords used were “Diabetes mellitus” “COVID-19”, “ACE 2” “Endothelial dysfunction” “Immune response” “Alveolar dysfunction” and “Pathophysiology”. The main alterations found were of the angiotensin-converting enzyme 2, dysregulated immune response, endothelial dysfunction, coagulopathy, treatment, and complications of diabetes mellitus. Therefore, these patients should pay special attention in the prevention of COVID-19 and the health systems must guarantee adequate treatment, attention, infrastructure, and services. La diabetes mellitus y la COVID-19 son problemas de salud pública globales que representan un reto para los sistemas de salud. La diabetes mellitus es una enfermedad crónica caracterizada por niveles elevados de glucosa. La COVID-19 es una infección causada por el virus SARS-CoV-2. La diabetes mellitus puede aumentar el desarrollo adverso de los pacientes con COVID-19. El objetivo fundamental de la presente revisión sistemática fue sintetizar los principales mecanismos conocidos que incrementan esta vulnerabilidad, resaltando su manejo apropiado. La importancia de esto recae en que una gran proporción de la población mundial es afectada por la diabetes mellitus. Los estudios realizados desde el inicio de la pandemia sobre la asociación entre estas enfermedades son considerables, sin embargo, aún queda mucho por conocer. La información disponible fue consultada mediante una búsqueda bibliográfica en español e inglés en las bases de datos PubMed, Google Scholar y revistas como Lancet y Nature hasta el 18 de junio del 2021. Las palabras claves que se utilizaron para la búsqueda por separado y combinadas fueron “Diabetes mellitus”, “COVID-19”, “ACE 2”, “Disfunción endotelial” “Respuesta inmune”, “Disfunción alveolar” y “Fisiopatología”. Las principales alteraciones encontradas fueron de la enzima convertidora de angiotensina 2, la respuesta inmune desregulada, la disfunción endotelial, la coagulopatía, el tratamiento y las complicaciones preexistentes de la diabetes mellitus. Por lo tanto, estos pacientes deben prestar especial atención en la prevención de la COVID-19 y los sistemas de salud garantizarles un adecuado tratamiento, atención, infraestructura y servicios. REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora 2021-08-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artículo revisado por pares application/pdf https://ojs-remus.unison.mx/index.php/remus_unison/article/view/6 REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora; Número 6 (Agosto 2021); 29-40 spa https://ojs-remus.unison.mx/index.php/remus_unison/article/view/6/5 Derechos de autor 2021 REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora |
| institution |
REMUS |
| collection |
OJS |
| language |
spa |
| format |
Online |
| author |
Flores-Díaz, Andrea Hinojosa-Pérez, Botswana |
| spellingShingle |
Flores-Díaz, Andrea Hinojosa-Pérez, Botswana Diabetes mellitus and COVID-19: ¿A vicious cycle? |
| author_facet |
Flores-Díaz, Andrea Hinojosa-Pérez, Botswana |
| author_sort |
Flores-Díaz, Andrea |
| title |
Diabetes mellitus and COVID-19: ¿A vicious cycle? |
| title_short |
Diabetes mellitus and COVID-19: ¿A vicious cycle? |
| title_full |
Diabetes mellitus and COVID-19: ¿A vicious cycle? |
| title_fullStr |
Diabetes mellitus and COVID-19: ¿A vicious cycle? |
| title_full_unstemmed |
Diabetes mellitus and COVID-19: ¿A vicious cycle? |
| title_sort |
diabetes mellitus and covid-19: ¿a vicious cycle? |
| description |
Diabetes mellitus and COVID-19 are global health issues that represent a challenge for health systems. Diabetes mellitus is a disease that is characterized by elevated glucose levels. COVID-19 is an infection caused by the virus SARS-CoV-2. Diabetes mellitus may increase the adverse outcome in patients with COVID-19. The main aim of the present systematic review was to summarize the principal known mechanisms that increment this vulnerability, highlighting special measures. The importance of this lies in the fact that a large proportion of the world's population is affected by diabetes mellitus. The studies achieved since the beginning of the pandemic on the association between these diseases are substantial, however, much remains to be known. The information available was consulted in spanish and english through a literature review in databases as PubMed, Google Scholar and journals like Lancet and Nature till June 18, 2021. The main keywords used were “Diabetes mellitus” “COVID-19”, “ACE 2” “Endothelial dysfunction” “Immune response” “Alveolar dysfunction” and “Pathophysiology”. The main alterations found were of the angiotensin-converting enzyme 2, dysregulated immune response, endothelial dysfunction, coagulopathy, treatment, and complications of diabetes mellitus. Therefore, these patients should pay special attention in the prevention of COVID-19 and the health systems must guarantee adequate treatment, attention, infrastructure, and services. |
| publisher |
REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora |
| publishDate |
2021 |
| url |
https://ojs-remus.unison.mx/index.php/remus_unison/article/view/6 |
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