Propolis, a Biological Resin with Healing Properties
Propolis, along with honey, royal jelly, beeswax and bee venom, is a bee product that has drawn great attention due to its pharmacological properties. Propolis is a resinous substance made by bees from exudates, resins and latices secreted from leaves and leave buds of plants. It is a very complex b...
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Universida de Sonora
2021
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oai:ojs2.127.0.0.1:article-382021-12-27T13:54:12Z Propolis, a Biological Resin with Healing Properties El propóleos, una Resina Biológica con Propiedades Curativas Lipovka, Yulia Alday, Efrain Velázquez, Carlos Propóleos Cáncer Propiedades antiproliferativas Propolis Cancer Antiproliferative propierties Propolis, along with honey, royal jelly, beeswax and bee venom, is a bee product that has drawn great attention due to its pharmacological properties. Propolis is a resinous substance made by bees from exudates, resins and latices secreted from leaves and leave buds of plants. It is a very complex biological matrix, with over 500 chemical constituents described to date. Propolis has different biological properties, anti-cancer activity being one of them. This article briefly describes the different types of bee products with a special focus on propolis and its chemical composition. Then, in the context of cancer biology, discusses the molecular events underlying the anti-cancer effects of propolis, identifying the key molecules involved. The effect of propolis on proliferation, cell cycle progression, apoptosis, migration of cancer cells and angiogenesis is reviewed. Propolis is a biological matrix with a great potential for isolation of chemicals with anti-cancer activity, which alone, or in combination, could represent an alternative for the development of new anti-cancer therapies. El propóleos, junto con la miel, la jalea real, la cera y el veneno de abejas, es considerado uno de los productos de colmena que ha generado gran interés por sus propiedades farmacológicas. El propóleos es una sustancia resinosa, elaborada por las abejas a partir de exudados, resinas y látex secretados por las hojas y brotes de plantas. Es una matriz biológica muy compleja, en la que se ha detectado la presencia de más de 500 sustancias químicas diferentes. Posee diversas propiedades biológicas, entre las cuales destaca su efecto anti-cancerígeno. Este artículo describe de una forma resumida los distintos productos de las abejas, poniendo énfasis en el propóleos y su composición química. Posteriormente, en el contexto de la biología del cáncer, se discuten los sucesos moleculares que subyacen el efecto anti-cancerígeno del propóleos, identificando las principales moléculas involucradas. Se describe la capacidad del propóleos de inhibir la proliferación, la progresión del ciclo celular y migración de células cancerígenas, así como de inducir apoptosis y suprimir la angiogénesis. El propóleos constituye una matriz biológica muy atractiva para el aislamiento de compuestos con actividad anti-cancerígena, que solos, o en conjunto, pudieran representar una alternativa para la elaboración de terapias contra el cáncer. Universida de Sonora 2021-12-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artículo revisado por pares application/pdf https://invurnus.unison.mx/index.php/INVURNUS/article/view/38 10.46588/invurnus.v16i1.38 INVURNUS; Vol. 16 Núm. 1 (2021): Vol. 16 No. 1 (Enero-Diciembre) 2021 2007-6185 2007-5421 spa https://invurnus.unison.mx/index.php/INVURNUS/article/view/38/42 Derechos de autor 2021 https://creativecommons.org/licenses/by-nc/4.0 |
| institution |
Invurnus |
| collection |
OJS |
| language |
spa |
| format |
Online |
| author |
Lipovka, Yulia Alday, Efrain Velázquez, Carlos |
| spellingShingle |
Lipovka, Yulia Alday, Efrain Velázquez, Carlos Propolis, a Biological Resin with Healing Properties |
| author_facet |
Lipovka, Yulia Alday, Efrain Velázquez, Carlos |
| author_sort |
Lipovka, Yulia |
| title |
Propolis, a Biological Resin with Healing Properties |
| title_short |
Propolis, a Biological Resin with Healing Properties |
| title_full |
Propolis, a Biological Resin with Healing Properties |
| title_fullStr |
Propolis, a Biological Resin with Healing Properties |
| title_full_unstemmed |
Propolis, a Biological Resin with Healing Properties |
| title_sort |
propolis, a biological resin with healing properties |
| description |
Propolis, along with honey, royal jelly, beeswax and bee venom, is a bee product that has drawn great attention due to its pharmacological properties. Propolis is a resinous substance made by bees from exudates, resins and latices secreted from leaves and leave buds of plants. It is a very complex biological matrix, with over 500 chemical constituents described to date. Propolis has different biological properties, anti-cancer activity being one of them. This article briefly describes the different types of bee products with a special focus on propolis and its chemical composition. Then, in the context of cancer biology, discusses the molecular events underlying the anti-cancer effects of propolis, identifying the key molecules involved. The effect of propolis on proliferation, cell cycle progression, apoptosis, migration of cancer cells and angiogenesis is reviewed. Propolis is a biological matrix with a great potential for isolation of chemicals with anti-cancer activity, which alone, or in combination, could represent an alternative for the development of new anti-cancer therapies. |
| publisher |
Universida de Sonora |
| publishDate |
2021 |
| url |
https://invurnus.unison.mx/index.php/INVURNUS/article/view/38 |
| work_keys_str_mv |
AT lipovkayulia propolisabiologicalresinwithhealingproperties AT aldayefrain propolisabiologicalresinwithhealingproperties AT velazquezcarlos propolisabiologicalresinwithhealingproperties AT lipovkayulia elpropoleosunaresinabiologicaconpropiedadescurativas AT aldayefrain elpropoleosunaresinabiologicaconpropiedadescurativas AT velazquezcarlos elpropoleosunaresinabiologicaconpropiedadescurativas |
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