NMDA Encephalitis: Case report and literature review

Autoimmune encephalitis characterized by the presence of IgG antibodies to the GluR1 subunit of Nmethyl-D-Aspartate receptor (NMDAr) mainly affects women over 18 years old and is commonly associated with an ovarian teratoma. It was previously described as a paraneoplastic disease; however, it has be...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Islas-Serrano, Juan, Vildaurrazaga-García, Carlos Omar, Anaya-Castro, Diana Monica, Espinoza-Larios, Adolfo
বিন্যাস: Online
ভাষা:spa
প্রকাশিত: REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora 2020
অনলাইন ব্যবহার করুন:https://ojs-remus.unison.mx/index.php/remus_unison/article/view/22
ট্যাগগুলো: ট্যাগ যুক্ত করুন
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বিবরন
সংক্ষিপ্ত:Autoimmune encephalitis characterized by the presence of IgG antibodies to the GluR1 subunit of Nmethyl-D-Aspartate receptor (NMDAr) mainly affects women over 18 years old and is commonly associated with an ovarian teratoma. It was previously described as a paraneoplastic disease; however, it has been shown that it affects both genders and that the condition may be present without an underlying tumor. We present a case of a 20-year-old female who initially presented headaches, followed by behavioral changes. After that, she progressed to a catatonic state and central hypoventilation, requiring admission to intensive care. During her hospital stay, she presented autonomic dysfunction and dyskinesias. A serum diagnosis of anti-NMDAr encephalitis is made, starting immunosuppressive treatment with steroids, followed by rituximab. The patient had a remarkable improvement and complete recovery from the disease.